Fit-for-Purpose eCOA Design & Architecture

Every clinical trial carries its own rhythms, complexities, and hopes. Yet for too long, digital systems have forced studies into rigid structures that slow them down rather than propel them forward. At Datacubed, we believe technology should serve the protocol intuitively, elegantly, and without compromise. So we built an architecture designed for a simple truth: No two trials are the same, and your platform shouldn’t be either.

Our modular, compliance-first foundation bends to your protocol, scales with your enrollment, and adapts instantly to decentralized, hybrid, and site-based models. It is future-proof by design and engineered to evolve with science, not constrain it.

One Architecture, Infinite Study Designs A single foundation, purpose-built for every path your research takes.

Most platforms fracture when trials require flexibility, forcing separate workflows, separate builds, and separate validations. We took a different path. Datacubed runs everything on a single, unified architecture that gracefully adapts to the model you need today, and the one you will need tomorrow.

Decentralized trials

  • Remote-first workflows designed without friction
  • BYOD and provisioned device flexibility
  • Instant global scale
  • Every touchpoint crafted for clean, continuous data capture

Hybrid trials

  • A seamless blend of remote and on-site elements
  • Telehealth, scheduling, device management all built into the same fabric
  • Configurable at the protocol, country, and participant level

Site-based trials

  • Optimized clinical workflows for tablets and provisioned devices
  • Local regulatory alignment built into the architecture itself
  • Effortless interoperability with site systems

Across every model, Datacubed acts as the connective tissue of the trial, harmonizing data, devices, and workflows across regions, roles, and realities.

Engineered for Confidence at Any Scale

Scaling a trial shouldn’t introduce fragility. It should introduce momentum. Datacubed’s architectural backbone has been validated across some of the most complex global studies in the world. Behind the simplicity you see an engineering approach obsessively focused on reliability, compliance, and performance.

Our platform:

  • Complies with 21 CFR Part 11, HIPAA, and GDPR from day one
  • Powers trials across 60+ countries and 100+ languages
  • Delivers 99.9% uptime for global deployments
  • Operates under a QMS with audit-ready SOPs and documentation

Future-Proof by Design

When your study evolves, your technology should evolve with it.

Datacubed’s architecture allows you to:

  • Add new countries without redevelopment
  • Expand from site-based to decentralized without a rebuild
  • Integrate sensors and wearables without heavy engineering
  • Customize workflows and dashboards without code
  • Maintain compliance through every evolution

Build the Architecture Your Trial Deserves

A system should amplify your science, not dictate it. If you’re ready to launch faster, scale smarter, and future-proof your study from day one, let’s create the architecture that meets your protocol’s exact needs.

Architect Your Foundation

  • “I liked Datacubed because of the ease of use, and the fact that I could do the questions at a speed I felt comfortable with.”

    Usability Test Patient

  • “Datacubed continues to ask questions and involve sites and not only hears the feedback but implements changes to its product continually.”

    Karri Venn
    COO, Centricity Research

  • “They have not only embraced the needs of our study, but they have taken it upon themselves to identify ways to make their system more efficient, patient-friendly, and study appropriate.”

    Anonymous Sponsor
    MPH, VP, Program Manager & Clinical Operations, Clinical Trial Sponsor

  • “Overall, it’s been very positive, and sites are very excited to use our system!”

    Anonymous Sponsor
    Clinical Research Study Team, Academic Medical School

  • “We are using the geofencing technology for patients experiencing an infection that would typically result in an emergency care visit. By targeting facilities with an emergency department, we believe we will be able to track at least 95 percent of the medical visits brought on by the infection.”

    Anonymous Sponsor
    Director, Clinical Innovation, Top 10 Pharma

  • “In comparison to other eCOA developers, the Datacubed Health solution provides our study team with the flexibility, cost savings, and improved patient engagement of using the patient’s personal handheld device and provides the study team with real time access to patient responses and analytics.”

    Anonymous Sponsor
    Director, Clinical Development, Clinical Team Lead, Neurology and Ophthalmology Pharma

  • “The Admin Panel is quite intuitive, and development was simple.”

    Anonymous Sponsor
    Founder, CEO, Nutraceutical Company

  • “The Datacubed Health platform is really nice to look at and is intuitive for technology competency. It’s very pleasing to our international network.”

    Anonymous Sponsor
    Clinical Coordinator, Rare Disease, Alzheimers, Network Academic Medical Center

  • “The study represents one of the most important opportunities to understand Alzheimer’s disease. We are excited to partner with Datacubed Health in order to bring a new set of tools to interact with our participants and collect information outside of the typical research environment.”

    Anonymous Sponsor
    Principal Investigator, Academic Medical Center

  • “The gamification was a unique selling point for me. Also, having the opportunity to have a possibility if needed to discuss medical issues outside of the clinical team. Having someone from the medical team who could give insights and perspectives on oncology in particular.”

    Anonymous Sponsor
    Director, Clinical Innovation, Top 10 Pharma